Objectives: It is analysed the actual situation of the investigations related to cannabinoids substances, as well as their interaction with the organism, classification, therapeutics effects and their use in neurodegenerative diseases.
Methods: This study is based on the review of multiples scientific articles directly related with the cannabinoides substance and its synthetic derivates, with a special attention on the way the organism interacts and the effects the substances cause in it. Specifically, the study will get deep into the neuroantiinflammatory and analgesic effects of these substances, related with the neuroprotector effect in neurodegenerative diseases such as Alzheimer, Parkinson, Multiple Sclerosis and Amyotrophic Lateral Sclerosis.
Results: From thousands years, the Cannabis Sativa has been used by multiples cultures with different purposes such as joy, textile, analgesics etc. But is not till ends of the XX century when there are diverse scientific studies related with the Cannabis encouraged. The plant has 400 components, 60 of them belong to the cannabinoides group. The main ones are cannabinol, cannabidiol and tetrahidrocannabinol. With the discoverment of the cannabinoids substances, its derivates, and the receptors which interact with them, it is increased the therapeutic possibilities and remarking the neuroprotective effect which these substances contain.
Conclusions: It has been demostraded the huge potential of the cannabinoids as therapeutic substances apart from its analgesic and antiemetic uses, that is, neurodegenaritve diseases in which they can not only decrease its symptons but stop disease process. Another possible application could be in the oncologic area, being particularly intense the investigation’s activity realised the last 15 years.
Cannabis alters different cognitive functions such as memory, perception, attention, comprehension, language, orientation or executive function. These alterations have been described both in situations of consumption, either for recreational or medicinal reasons, and in experimental situations, either in human studies or in experimental animals. These alterations can be acute, derived from intoxication, or sustained over time due to prolonged consumption.
Berlin, das aufgrund seiner starken Wirtschafts- und Energiebeziehungen ein schwieriges Verhältnis zu Russland unterhält, verteidigt sich entschieden gegen eine militärische Aggression aus Moskau, entscheidet sich jedoch für den diplomatischen Weg, um Spannungen abzubauen. Der sozialdemokratische Bundeskanzler Olaf Scholz fordert von Russland "eindeutige Schritte" zur Deeskalation an der Grenze zur Ukraine. „Unmissverständliche Schritte Russlands zur Deeskalation sind sehr wichtig“, betonte die deutsche Bundeskanzlerin bei einer gemeinsamen Pressekonferenz mit Pedro Sánchez nach dem Treffen im Palacio de la Moncloa am Montag.
Scholz betont den Ernst der Lage, die eine „Gefahr für die Souveränität der Ukraine“ darstelle, für die er es für notwendig erachtet, „alles Mögliche zu tun“, um eine militärische Intervention zu vermeiden. „Die Unverletzlichkeit der Grenzen ist etwas, das wir respektieren müssen“, betont die Kanzlerin, die davor gewarnt hat, dass die klare Botschaft Deutschlands lautet, dass „jede Bedrohung der Integrität der Ukraine einen hohen Preis haben wird“.
CBD is an extract from the hemp plant from which cannabis is made. But unlike the tetrahydrocannabinol (THC) component of marijuana, CBD does not produce the “high” associated with cannabis.
This is because CBD and THC affect different receptors within the endocannabinoid system. This system reacts to the cannabinoids produced by our bodies, which, in turn, regulate how we feel and experience pain. Much of the scientific research so far has focused on whether the CBD compounds found in marijuana can intensify the effects of cannabinoids and therefore relieve chronic pain and inflammation.
To date, studies have indicated that medical marijuana reduces chronic pain in people with painful conditions such as arthritis. Additionally, CBD can help people with restless leg syndrome (RLS), a condition that disrupts sleep with uncontrolled leg movements. RLS is often an accompanying symptom of varicose veins. By increasing the body’s dopamine levels, CBD could give RLS and varicose vein patients the good rest they crave.
Hemp oil in another form has been used by patients with varicose veins to reduce the discomfort and appearance of varicose veins. Made from hemp seeds, hemp oil does not contain THC or CBD, but does contain omega-3 fatty acids that thin the blood. As the blood thins as it runs through the veins, the appearance of varicose veins decreases.
It has also been reported that hemp oil can stop the itching that varicose veins sometimes cause, as well as make spider veins less visible. Like other essential oils and lotions, hemp oil is not a cure for varicose veins. For that, you need treatment from a vein specialist.
If you decide to take a CBD supplement for varicose vein pain, check with your doctor to make sure the substance does not interact negatively with medications they may prescribe for other conditions.